Pre-Formulation: The pre-formulation stage involves selecting the active pharmaceutical ingredient (API) and excipients for the capsule formulation. Compatibility studies and formulation development are conducted to determine the appropriate composition and dosage strength.
Formulation: Once the API and excipients are selected, the formulation process involves blending and mixing them in specific ratios to achieve a homogeneous mixture that ensures the desired drug release profile and stability.
Gelatin-based capsules, the gelatin is processed by mixing it with plasticizers and other additives to enhance the capsule's flexibility and stability. The gelatin mixture is then formed into sheets, which are further processed into capsules using encapsulation machines.
- John Henry
Vegetarian capsules are made from plant-based materials, typically hydroxypropyl methylcellulose (HPMC) or pullulan. These materials are processed into a capsule shell using similar techniques to gelatin capsules
Capsule manufacturing requires precision, adherence to Good Manufacturing Practices (GMP), and compliance with regulatory guidelines to ensure the production of safe, effective, and reliable dosage forms. The process involves multiple stages, from formulation to filling, sealing, printing, quality control, and packaging, to produce capsules that deliver medications accurately and conveniently for patients
Capsule manufacturing requires precision, adherence to Good Manufacturing Practices (GMP), and compliance with regulatory guidelines to ensure the production of safe, effective, and reliable dosage forms. The process involves multiple stages, from formulation to filling, sealing, printing, quality control, and packaging, to produce capsules that deliver medications accurately and conveniently for patients.
Amoxicillin capsules