Capsules Manufacturing

Best innovations PHARMACEUTICAL MANUFACTURING

Pre-Formulation: The pre-formulation stage involves selecting the active pharmaceutical ingredient (API) and excipients for the capsule formulation. Compatibility studies and formulation development are conducted to determine the appropriate composition and dosage strength.

Formulation: Once the API and excipients are selected, the formulation process involves blending and mixing them in specific ratios to achieve a homogeneous mixture that ensures the desired drug release profile and stability.

Gelatin Capsules:

 Gelatin-based capsules, the gelatin is processed by mixing it with plasticizers and other additives to enhance the capsule's flexibility and stability. The gelatin mixture is then formed into sheets, which are further processed into capsules using encapsulation machines.

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Vegetarian Capsules:

 Vegetarian capsules are made from plant-based materials, typically hydroxypropyl methylcellulose (HPMC) or pullulan. These materials are processed into a capsule shell using similar techniques to gelatin capsules

Process
Capsule Shell Preparation
Filling the Capsules
Sealing and Printing
Quality Control and Packaging

Capsule manufacturing requires precision, adherence to Good Manufacturing Practices (GMP), and compliance with regulatory guidelines to ensure the production of safe, effective, and reliable dosage forms. The process involves multiple stages, from formulation to filling, sealing, printing, quality control, and packaging, to produce capsules that deliver medications accurately and conveniently for patients

Working Process

01
Step

Capsule Shell Preparation

Capsule shell preparation involves mixing gelatin or plant-based materials, adding plasticizers, molding into capsule shapes, and drying
02
Step

Filling the Capsules

Capsule filling machines are used to fill the formulated powders or granules into the capsule shells. These machines can be semi-automatic or fully automated, and they ensure accurate and efficient filling of the capsules.
03
Step

Sealing and Printing

Sealing: Capsule halves are joined and sealed to prevent leakage, using heat sealing for gelatin or self-locking for vegetarian capsules.

Printing: Capsules are marked with product details for identification and traceability.
04
Step

Quality Control and Packaging

Quality Control : Rigorous measures ensure capsules meet standards for quality, safety, and efficacy, including tests for weight, content uniformity, disintegration, and dissolution.

Packaging: Capsules that pass quality control are packaged in suitable containers, like blister packs or bottles, with appropriate labeling and patient information.

More of Capsule manufacturing

Capsule manufacturing requires precision, adherence to Good Manufacturing Practices (GMP), and compliance with regulatory guidelines to ensure the production of safe, effective, and reliable dosage forms. The process involves multiple stages, from formulation to filling, sealing, printing, quality control, and packaging, to produce capsules that deliver medications accurately and conveniently for patients.

 

Project Information

Amoxicillin capsules 

Client Name

Confia pharmacy

Category

capsules

Start Time

01 Jan, 2024

End Time

26 Apr, 2024

Budget

₹ 200000

Location

Rohini Delhi

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